CHRIS SHAW partial publications list (PDFs below!)

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C. Shaw's "Amphibian skin peptides and venom research."

1. Salmon, AL, Johnsen, AH., Bienert, M., McMurray, G., Nandha, KA, Bloom, SR. and Shaw, C. (2000) Isolation, structural characterization and biological activity of a novel neuromedin U analog from the defensive skin scretion of the Australasian tree frog, Litoria caerulea. J. Biol.Chem., 275, 4549-4554.

2. Salmon AL, Cross LJM, Irvine AE, Lappin, TRJ, Dathe, M, Krause, G, Canning, P, Thim, L, Beyermann, M, Rothemund, S, Bienert, M. and Shaw, C. (2001) Peptide leucine arginine, a potent immunomodulatory peptide isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens. J. Biol. Chem., 276, 10145-10152.

3. Chen TB, Orr DF, Bjourson AJ, McClean, S, O’Rourke, M, Hirst, DG, Rao, P. and Shaw, C. (2002) Novel bradykinins and their precursor cDNAs from European yellow-bellied toad (Bombina variegata) skin. Eur. J. Biochem., 269, 4693-4700.

4. Chen TB, Orr DF, Bjourson AJ, McClean, S, O’Rourke, M, Hirst, DG, Rao, P. and Shaw, C. (2002) Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis). Peptides, 23, 1547-1555.

5. McClean S, Robinson RC, Shaw C, et al. (2001) Characterisation and determination of indole alkaloids in frog-skin secretions by electrospray ionisation ion trap mass spectrometry. Rapid Commun. Mass Spec. 16, 346-354.

6. Chen, T., Bjourson, A.J., Orr, D.F., Kwok H., Rao, P., Ivanyi C. and Shaw, C. (2002) Unmasking venom gland transcriptomes in reptile venoms. Anal. Biochem., 311, 152-156.

7. Chen, T., Farragher, S., Bjourson, A.J., Orr, D.F., Rao, P. and Shaw, C. (2003) Granular gland transcriptomes in stimulated amphibian skin secretions. Biochem. J. 371, 125-130.

8. Chen, T, Bjourson, AJ, McClean, S, Orr, DF, O’Kane, EJ, Rao, P. and Shaw, C. (2003) Cloning of maximakinin precursor cDNAs from the Chinese toad, Bombina maxima, venom. Peptides, 24, 853-861.

9. Chen, T. and Shaw, C. (2003) Identification and molecular cloning of novel trypsin inhibitor analogs from the dermal venom of the Oriental fire-bellied toad (Bombina orientalis) and the European yellow-bellied toad, (Bombina variegata). Peptides, 24, 873-880.

10.Li, L, Bjourson, AJ, He, J, Cai, G, Rao, P. and Shaw, C. (2003) Bradykinins and their cDNA from the piebald odorous frog, Odorrana schmackeri, skin. Peptides, 24, 863-872.

11. Chen, T., Folan, R., Kwok, H.F., O’Kane, E.J., Bjourson, A.J. and Shaw, C. (2003) Isolation of scorpion (Androctonus amoreuxi) alpha-neurotoxins and parallel cloning of their respective cDNAs from a single sample of venom. Regul. Peptides, 115, 115-121.

12. Chen, T., Tang, L. and Shaw, C. (2003) Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library. Regul. Peptides, 116, 139-146.

13. Chen, T. and Shaw, C. (2003) Cloning of the (Thr6)-phyllokinin precursor from Phyllomedusa sauvagei skin confirms a non-consensus tyrosine 0-sulfation motif. Peptides, 24, 1123-1130.

14. Chen, T., O’Rourke, M., Orr, D.F., Coulter, D.J.M., Hirst, D.G., Rao, P. and Shaw, C. (2003) Kinestatin: a novel bradykinin B2 receptor antagonist peptide from the skin secretion of the Chinese toad, Bombina maxima. Regul. Peptides, 116, 147-154.

15. Zheng, H., McClean, S., Ojha, P.C., Black, N.D., Hughes, J.G. and Shaw, C. (2003) Heuristic charge assignment for deconvolution of electrospray ionization mass spectra. Rapid Comm. Mass Spec., 17, 1-8.

16. Chen, T., Orr, D.F., O’Rourke, M., McGlynn, C., Bjourson, A.J., McClean, S., Hirst, D.G., Rao, P. and Shaw, C. (2004) Pachymedusa dacnicolor tryptophyllin-1 (PdT-1): structural characterization, pharmacological activity and cloning of precursor cDNA. Regul. Peptides, 117, 25-32.

17. Marenah, L., Flatt, P.R., Orr, D.F., McClean, S., Shaw, C. and Abdel-Wahab, Y.H.A. (2004) Skin secretion of the toad, Bombina variegata, contains multiple insulin-releasing peptides, including bombesin and entirely novel insulinotropic structures. Biol. Chem., 385, 315-321.

18. Marenah, L., Shaw, C., Orr, D.F., McClean, S., Flatt, P.R. and Abdel-Wahab, Y.H.A. (2004) Isolation and characterisation of an unexpected class of insulinotropic peptides from the skin of the frog, Agalychnis litodryas. Regul.Peptides, 120, 33-38.

19. O’Rourke, M., Chen, T., Hirst, D.G., Rao, P. and Shaw, C. (2004) The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima. Regul. Peptides, 121, 65-72.

20. Marenah, L., Flatt, P.R., Orr, D.F., McClean, S., Shaw, C. and Abdel-Wahab, Y.H.A. (2004) Brevinin-1 and multiple insulin-releasing peptides in the skin of the frog, Rana palustris. J. Endocrinol., 181, 347-354.

21. Marenah, L., McClean, S., Flatt, P.R., Orr, D.F., Shaw, C. and Abdel-Wahab, Y.H.A. (2004) Novel insulin-releasing peptides in the skin of the frog Phyllomedusa trinitatus includes 28 amino acid peptides from the dermaseptin IV precursor. Pancreas, 29, 110-115.

22. Zheng, H., Ojha, P.C., McClean, S., Black, N.D., Hughes, J.G. and Shaw, C. (2004) Peptidomic pattern analysis and taxonomy of amphibian species. Computational and Information Science, First International Symposium, Shanghai, China, vol. 3314, 498-503.

23. Chen, T., Xue, Y., Zhou, M. and Shaw, C. (2005) Molecular cloning of mRNA from toad granular gland secretion and lyophilized skin: identification of Bo8 - a novel prokineticin from Bombina orientalis. Peptides, 26, 377-383.

24. Chen, T., Scott, C., Tang, L., Zhou, M. and Shaw, C. (2005) The structural organization of aurein precursor cDNAs from the skin secretion of the Australian green and gold bell frog, Litoria aurea. Regul. Peptides, 128, 75-83.

25. Chen, T., Walker, B., Zhou, M. and Shaw, C. (2005) Molecular cloning of a novel putative potassium channel-blocking neurotoxin from the venom of the North African scorpion, Androctonus amoreuxi. Peptides, 26, 731-736.

26. Graham, C., Irvine, A.E., McClean, S., Richter, S.C., Flatt, P.R. and Shaw, C. (2005) Peptide Tyrosine Arginine, a potent immunomodulatory peptide isolated and structurally-characterized from the skin secretion of the dusky gopher frog, Rana sevosa. Peptides, 26, 737-743.

27. Chen, T., Walker, B., Zhou, M. and Shaw, C. (2005) Dermatoxin and phylloxin from the waxy monkey frog, Phyllomedusa sauvagei: cloning of precursor cDNAs and structural characterization from lyophilized skin secretion. Regul. Pept. 129, 103-108.

28. Chen, T., Gagliardo, R., Walker, B., Zhou, M. and Shaw, C. (2005) Partial structure of the phylloxin gene from the giant monkey frog, Phyllomedusa bicolor: parallel cloning of precursor cDNA and genomic DNA from lyophilized skin secretion. Peptides 26, 2624-2628.

29. Chen, T., Reid, C,N., Walker, B., Zhou, M. and Shaw, C. (2005) Kassinakinin S: a novel histamine-releasing heptadecapeptide from Kassina senegalensis skin secretion - isolation, structural characterization and cloning of precursor cDNA. Biochem. Biophys. Res. Commun. 337, 474-480.

30. Chen,T., O’Rourke, M., McKenna, J., Hirst, D.G. and Shaw, C. (2005) Maximakinin, a bradykinin-related peptide from toad venom: biotransformation by mammalian kallikrein and salivary proteases. J. Pept. Res. 66, 106-113.

31. Marenah, L., Flatt, PR., Orr, DF., Shaw, C. and Abdel-Wahab, YHA. (2005) Isolation and structural characterization of a novel rugosin A-like insulinotropic peptide from the skin secretions of Rana saharica. Peptides 26, 2117-2123.

32. Zhou, M., Chen, T., Walker, B. and Shaw, C. (2005) Novel frenatins from the skin of the Australasian giant white-lipped tree frog, Litoria infrafrenata: cloning of precursor cDNAs and identification in defensive skin secretion. Peptides 26, 2445-2451.

33. Chen, T., Zhou, M., Lorimer, J., Rao, P., Walker, B. and Shaw, C. (2007) Cloning from tissue surrogates: antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs. Genomics 87, 638-644.

34. Graham, R.L.J., McClean, S., O’Kane, E.J., Theakston, D. and Shaw, C. (2005) Adenosine in the venoms from viperinae snakes of the genus Bitis: identification and quantitation using LC/MS and CE/MS. Biochem. Biophys. Res. Commun. 333, 88-94.

35. Zhou, M., Chen, T. Walker, B. and Shaw, C. (2006) Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by “shotgun” cDNA cloning and sequence analysis. Peptides 27, 36-41.

36. Abdel-Wahab, Y.H.A., Marenah, L., Orr, D.F., Shaw, C. and Flatt, P.R. (2005) Isolation and structural characterisation of a novel 13-amino acid insulin-releasing peptide from the skin secretion of Agalychnis calcarifer. Biol. Chem. 386, 581-587.

37. Marenah, L., Flatt, P.R., Orr, D.F., Shaw, C. and Abdel-Wahab, Y.H.A. (2005) Characterization of naturally-occurring peptides in the skin secretions of Rana pipiens frog reveal pipinin-1 as the novel insulin-releasing agent. J. Pept. Res. 66, 204-210.

38. Graham, R.L.J., Graham, C., McClean, S., Chen, T., O,Rourke, M., Hirst, D., Theakston, D. and Shaw, C. (2005) Identification and functional analysis of a bradykinin inhibitory peptide in the venoms of New World Crotalinae pit vipers. Biochem. Biophys. Res. Commun. 338, 1587-1592.

39. Chen, T., Kwok, H. F., Ivanyi, C. and Shaw, C. (2006) Isolation and cloning of exendin precursor cDNAs from single samples of venom from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum). Toxicon 47, 288-295.

40. Graham, C., Richter, S. C., McClean, S., O’Kane, E., Flatt, P. R. and Shaw, C. (2006) Histamine-releasing and antimicrobial peptides from the skin secretions of the Dusky Gopher frog, Rana sevosa. Peptides 27, 1313-1319.

41. Marenah, L., Flatt, PR, Orr, DF, Shaw, C. and Abdel-Wahab, YHA. (2006) Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins 1 and 1B and brevinins 1E and 2EC with novel insulin releasing activity. J. Endocrinol. 188, 1-9.

42. Quinn, GAP, Heymans, R., Rondaj, F., Shaw, C. and de Jong-Brink, M. (2006) Schistosoma mansoni dermaseptin-like peptide: structural and functional characterization. J. Parasitol. 91, 1340-1351.

43. Zhou, M., Chen, T., Walker, B. and Shaw, C. (2006) Lividins: novel antimicrobial peptide homologs from the skin secretion of the Chinese Large Odorous frog, Rana (Odorrana) livida: identification by “shotgun” cDNA cloning and sequence analysis. Peptides 27, 2118-2123..

42. Zhou, M., Liu, Y., Chen, T., Fang, X., Walker, B. and Shaw, C. (2006) Components of the peptidome and transcriptome persist in lin wa pi: the dried skin of the Heilongjiang Brown frog (Rana amurensis) as used in Traditional Chinese medicine. Peptides 27, 2688-2694..

43. Chen, T., Zhou, M., Gagliardo, R., Walker, B. and Shaw, C. (2006) Elements of the granular gland peptidome and transcriptome persist in air-dried skin of the South American orange-legged leaf frog, Phyllomedusa hypocondrialis. Peptides 27, 2129-2136..

44. Chen, T., Zhou, M., Rao, P., Walker, B. and Shaw, C. (2006) The Chinese bamboo leaf odorous frog (Odorrana versabilis) and North American Rana frogs share the same families of skin antimicrobial peptides. Peptides 27, 1738-1744.

45. Chen, T., Zhou, M., Walker, B., Harriot, P., Mori, K., Miyazato, M., Kangawa, K. and Shaw, C. (2006) Structural and functional analogs of the novel mammalian neuropeptide, neuromedin S (NmS), in the dermal venoms of Eurasian bombinid toads. Biochem. Biophys. Res. Commun. 345, 377-384.

46. Thompson, AH,. Bjourson, AJ., Shaw, C. and McClean, S. (2006) Bradykinin-related peptides from Phyllomedusa hypochondrialis azurea: mass spectrometric structural characterization and cloning of precursor cDNAs. Rapid Comm. Mass Spec. 20, 3780-3788.

47. Zhou, J., McClean, S., Thompson, A., Zhang, Y., Shaw, C., Rao, P. and Bjourson, AJ. (2006) Purification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri. Peptides 27, 3077-3084.

48. Zhou, J., Bjourson, A.J., Coulter, D.J.M., Chen, T., Shaw, C., O’Rourke, M., Hirst, D.G., Zhang, Y., Rao, P. and McClean, S. (2007) Bradykinin-related peptides, including a novel structural variant, (Val1)-bradykinin, from skin secretion of Guenther's frog, Hylarana guentheri and their molecular precursors. Peptides 28, 781-789.

49. McCrudden, CM, Zhou, M., Chen, T., O’Rourke, M., Walker, B., Hirst, D. and Shaw, C. (2007) The complex array of bradykinin-related peptides (BRPs) in the peptidome of pickerel frog (Rana palustris) skin secretion is the product of transcriptional economy. Peptides 28, 1275-1281.

50. Kwok, HF., Chen, T., O’Rourke, M., Ivanyi, C., Hirst, D. and Shaw, C. (2008) Helokinestatin: a novel bradykinin B2 receptor antagonist decapeptide from lizard venom. Peptides 29, 65-72.

51. Sin, Y., Zhou, M., Chen, W., Wang, L., Chen, T., Walker, B. and Shaw, C. (2008) Skin bradykinin-related peptides and their biosynthetic precursors (kininogens): comparisons between various taxa of Chinese and North American ranid frogs. Peptides 29, 393-403.

52. Thompson, AH, Bjourson, AJ, Orr, DF, Shaw, C. and McClean, S. (2007) Amphibian skin secretomics: application of parallel quadrupole time-of-flight mass spectrometry and peptide precursor cDNA cloning to rapidly characterize the skin secretory peptidome of Phyllomedusa hypochondrialis azurea: discovery of a novel peptide family, the hyposins. J. Proteome Res. 6, 3604-3613.

53. Graham, R.L.J., Graham, C., Theakston, D., McMullan, G. and Shaw, C. (2007) Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography. Toxicon 51, 121-129.

54. 2007_Peptides_Rana palustris_Rapid identification of precursor cDNA

55. Song, G., Zhou, M., Chen, W., Chen, T., Walker, B. and Shaw, C. (2008) HV-BBI - a novel amphibian skin Bowman-Birk-like trypsin inhibitor. Biochem. Biophys. Res. Comm. 372, 191-196.

56. Quan, Z., Zhou, M., Chen, W., Chen, T., Walker, B. and Shaw, C. (2008) Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors. Peptides (in press - available on-line).

57. Wang, L., Zhou, M., McClelland, A., Reilly, A., Chen, T., Gagliardo, R., Walker, B. and Shaw, C. (2008) Novel dermaseptin, adenoregulin and caerin homologs from the Central American red-eyed leaf frog, Agalychnis callidryas, revealed by functional peptidomics of defensive skin secretion. Biochimie (in press).

58. Wang, L., Zhou, M., Wei, L., Reid, C., Smyth, A., Boyd, S., Chen, T., Walker, B. and Shaw, C. (2008) Kasseptins: a novel structural class of antimicrobial and histamine-releasing peptides from the defensive skin secretions of the African hyperoliid frogs, Kassina senegalensis and Kassina maculata. Mol. Immunol. (submitted).