Valerie Clark's Publications

	König, E., V. C. Clark,* C. Shaw and O. R. P. Bininda-Emonds. 2012. Molecular cloning of skin peptide precursor-encoding cDNAs from tibial gland secretion of the Giant Monkey Frog, Phyllomedusa bicolor (Hylidae, Anura). Peptides, 38: 371-376. PDF
	Clark, V. C., L. Harinantenaina, M. Zeller, W. Ronto, J. Rocca, A. T. Dossey, D. Rakotondravony, D. G. I. Kingston and C. Shaw. "An Endogenous Bile Acid and Diet-Sequestered Sucrose from Skin Secretions of Alkaloid-Sequestering Poison Frogs." Journal of Natural Products,* 75(3): 473-478. SUPPORTING INFORMATION PDF.
	Clark, V. C. 2010. Collecting arthropod and amphibian secretions for chemical analyses. Behavioral and Chemical Ecology. W. Zhang and H. Liu. New York, Nova Science Publishers, Inc.: 1-46.
	Means, D. B., Duellman, W. E., and V. C. Clark. 2008. Ovipositing behavior of the egg-brooding frog Stefania ayangannae (Anura, Hemiphractidae). Phyllomedusa. 7(2): 143-148. Journal Cover!
	Soriano, E. V., V. C. Clark and S. E. Ealick. 2007. Structures of human deoxycytidine kinase product complexes.Acta Crystallographica D63: 1201-1207.
	Clark, V. C., V. Rakotmalala, O. Ramilijoana, L. Abrell and B. L. Fisher. 2006. Individual variation in alkaloid content of poison frogs of Madagascar (Mantella; Mantellidae). Journal of Chemical Ecology*. 32: 2219-2233. (Supp. Info,-- Chromatograms)
	Clark, V. C., C. J. Raxworthy, V. Rakotomalala, P. Sierwald, and B. L. Fisher. 2005. Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics. Proceedings of the National Academy of Sciences USA. 102:*11617-11622. (Supporting information-- Table 3, frog alkaloids & Table 4, frog diet) Link to REFERENCES page
	Daly, J. W., H. M. Garraffo, T. F. Spande, V. C. Clark, J. Ma, H. Ziffer and J. F. Cover Jr. 2003. Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates. Proceedings of the National Academy of Sciences USA. 100*: 11092-11097.
	Clark, V. C. 2001. “Rana heckscheri—Ectoparasites.” Natural History Notes. Herpetological Review. 32(1): 36.
	Clark, V. C. 1998. Frog Skin Secretions. Reptile Hobbyist. 3(5): 78-82.
	Acknowledgements in Publications
	Hutchinson, D. A., A. Mori, A. H. Savitzky, G. M. Burghardt, et al. 2007. The Dietary Sequestration of Defensive Steroids in Nuchal Glands of the Asian Snake Rhabdophis tigrinus. Proceedings of the National Academy of Sciences USA. 104(7): 2265-2270.
	Daly, J. W., T. F. Spande and H. M. Garraffo. 2005. Alkaloids from Amphibian Skin: A Tabulation of Over Eight-Hundred Compounds. Journal of Natural Products. 68(10): 1556-1575. (Supporting Information)
	Daly, J. W., T. Kaneko, et al. 2002. Bioactive alkaloids of frog skin: Combinatorial bioprospecting reveals that pumiliotoxins have an arthropod source. Proceedings of the National Academy of Sciences USA. 99(22): 13996-14001.

To request reprints, e-mail me or click on links above.

"Fig. 1. Mantella poison frogs and their putative arthropod prey that contain the same defensive alkaloids. (a) M. madagascariensis (shown actual size). (b) M. bernhardi.(c) M. baroni.(d) R. purpureus.(e) T. electrum.(f) A. grandidieri. (Scale bars, 1 mm.) "

"Fig. 2. Known poison frog alkaloids detected in Malagasy arthropods (see Table 1). (a) Alkaloids detected in ants. (b) Alkaloids detected in the millipede R. purpureus. Asterisk indicates the branch point in the carbon skeleton of 217B."

Figures 1 and 2 reproduced from Clark, V. C.*, C. J. Raxworthy, V. Rakotomalala, P. Sierwald, and B. L. Fisher. 2005. Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics. Proceedings of the National Academy of Sciences USA. 102:11617-11622.